US 11,999,753 B2
Tetrahydropyridopyrimidine pan-KRas inhibitors
Xiaolun Wang, San Diego, CA (US); Anthony Ivetac, San Diego, CA (US); Svitlana Kulyk, San Diego, CA (US); John David Lawson, Carlsbad, CA (US); Matthew Arnold Marx, San Diego, CA (US); and Christopher Ronald Smith, San Diego, CA (US)
Assigned to MIRATI THERAPEUTICS, INC., San Diego, CA (US)
Filed by Mirati Therapeutics, Inc., San Diego, CA (US)
Filed on Dec. 16, 2021, as Appl. No. 17/553,224.
Claims priority of provisional application 63/126,350, filed on Dec. 16, 2020.
Claims priority of provisional application 63/158,119, filed on Mar. 8, 2021.
Claims priority of provisional application 63/164,345, filed on Mar. 22, 2021.
Prior Publication US 2022/0194961 A1, Jun. 23, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 471/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01)
CPC C07D 519/00 (2013.01) [A61P 35/00 (2018.01); C07D 471/04 (2013.01)] 5 Claims
 
1. A compound selected from:

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and a pharmaceutically acceptable salt thereof.