US 11,999,708 B1
Thiazole tethered organoselenides as 5-lipoxygenase inhibitors
Saad Shaaban, Al-Ahsa (SA); Hussein Ba-Ghazal, Al-Ahsa (SA); Mohamed Alaa Mohamed, Al-Ahsa (SA); and Abeer M. Ashmawy, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Feb. 28, 2024, as Appl. No. 18/590,133.
Int. Cl. C07D 277/34 (2006.01); A61K 31/427 (2006.01)
CPC C07D 277/34 (2013.01) [A61K 31/427 (2013.01)] 17 Claims
 
1. A compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
R is selected from the group consisting of

OG Complex Work Unit Chemistry
methyl, ethyl, butyl, pentyl, and hexyl; and
each X is the same or different and is H or COOMe.