US 11,998,608 B2
Polysaccharide and methods
John McGiven, Surrey (GB); Laurence Howells, Surrey (GB); Lucy Duncombe, Surrey (GB); David Bundle, Edmonton (CA); Satadru Sekhar Mandal, Edmonton (CA); and Susmita Sarkar, Edmonton (CA)
Assigned to THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS, (GB); and THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, (CA)
Filed by THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS, Surrey (GB); and THE GOVERNORS OF THE UNIVERSITY OF ALBERTA, Edmonton (CA)
Filed on May 11, 2021, as Appl. No. 17/316,944.
Application 17/316,944 is a continuation of application No. 16/347,550, granted, now 11,033,632, previously published as PCT/GB2017/053322, filed on Nov. 3, 2017.
Claims priority of application No. 1618635 (GB), filed on Nov. 4, 2016.
Prior Publication US 2021/0330799 A1, Oct. 28, 2021
Int. Cl. A61K 47/61 (2017.01); A61K 9/19 (2006.01); A61K 39/02 (2006.01); C07H 5/06 (2006.01); C07H 15/18 (2006.01); G01N 33/53 (2006.01); G01N 33/569 (2006.01); G01N 33/58 (2006.01); A61K 39/00 (2006.01)
CPC A61K 47/61 (2017.08) [A61K 9/19 (2013.01); A61K 39/098 (2013.01); C07H 5/06 (2013.01); C07H 15/18 (2013.01); G01N 33/5308 (2013.01); G01N 33/56911 (2013.01); G01N 33/582 (2013.01); A61K 2039/6031 (2013.01); G01N 2333/23 (2013.01); G01N 2400/00 (2013.01)] 17 Claims
 
1. A diagnostic conjugate comprising a trisaccharide consisting of three units of 4,6-dideoxy-4-formamido-α-D-mannopyranose and comprising only C1-C2 links or comprising a disaccharide consisting of two units of 4,6-dideoxy-4-formamido-α-D-mannopyranose joined by a C1-C2 link, wherein the trisaccharide or disaccharide is linked to a non-saccharide carrier via the reducing end and wherein the non-saccharide carrier comprises a protein, surface, or bead that allows the detection of the presence of an antibody in a sample.