US 11,998,559 B2
Agent for preventing or ameliorating alzheimer's disease
Kaori Takahashi, Tokyo (JP); Katsuyuki Mukai, Tokyo (JP); Yasuyuki Igarashi, Tokyo (JP); and Kohei Yuyama, Sapporo (JP)
Assigned to DAICEL CORPORATION, Osaka (JP)
Appl. No. 16/756,978
Filed by DAICEL CORPORATION, Osaka (JP)
PCT Filed Oct. 3, 2018, PCT No. PCT/JP2018/037018
§ 371(c)(1), (2) Date Apr. 17, 2020,
PCT Pub. No. WO2019/078005, PCT Pub. Date Apr. 25, 2019.
Claims priority of application No. 2017-201880 (JP), filed on Oct. 18, 2017.
Prior Publication US 2021/0121490 A1, Apr. 29, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/7032 (2006.01); A61P 25/28 (2006.01)
CPC A61K 31/7032 (2013.01) [A61P 25/28 (2018.01)] 7 Claims
 
1. A method for ameliorating cognitive function in Alzheimer's disease to a person in need of amelioration of Alzheimer's disease and cognitive function, comprising a step of administering an effective amount of a ceramide to the person,
wherein the ceramide is derived from tuber of Amorphophallus konjac and wherein the ceramide comprises a glucosylceramide of 4,8-sphingadienine.