US 11,998,530 B2
Micelle comprising benzimidazole-carbohydrate conjugate compound, preparation method thereof and use thereof as anticancer agent or antiviral agent comprising the same
Taisun Kim, Gangwon-do (KR); Keumsoo Song, Gangwon-do (KR); and Junghun Kim, Seoul (KR)
Assigned to BIOMETRIX TECHNOLOGY INC., Gangwon-Do (KR)
Filed by BIOMETRIX TECHNOLOGY INC, Gangwon-do (KR)
Filed on Dec. 7, 2021, as Appl. No. 17/544,514.
Claims priority of application No. 10-2021-0114230 (KR), filed on Aug. 27, 2021.
Prior Publication US 2023/0248702 A1, Aug. 10, 2023
Int. Cl. A61K 31/4184 (2006.01); A61K 9/107 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01)
CPC A61K 31/4184 (2013.01) [A61K 9/1075 (2013.01); A61K 47/549 (2017.08); A61P 35/00 (2018.01)] 12 Claims
 
1. A micelle comprising a benzimidazole-carbohydrate conjugate compound represented by the following chemical formula 1 and a benzimidazole-ammonium compound represented by the following chemical formula 1b:

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wherein, the —NH—R1 moiety has one of the following structures:

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the benzimidazole moiety has one of the following structures:

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and
Y− is a conjugate base of acid (H+) and is selected from Cl−, Br−, I−, F−, NO3−, CH3COO−, HCOO−, HCO3−, CO32−, H2PO4−, HPO42−, HSO4−, SO42−, or ClO4−.