US 11,998,385 B2
Methods and systems for investigating blood vessel characteristics
Laurence Rouet, Paris (FR); Hernán Guillermo Morales Varela, Suresnes (FR); and Constance Marie Anne Fourcade, Suresnes (FR)
Assigned to KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
Appl. No. 17/423,871
Filed by KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
PCT Filed Jan. 13, 2020, PCT No. PCT/EP2020/050617
§ 371(c)(1), (2) Date Jul. 18, 2021,
PCT Pub. No. WO2020/151965, PCT Pub. Date Jul. 30, 2020.
Claims priority of application No. 19290006 (EP), filed on Jan. 24, 2019.
Prior Publication US 2022/0096048 A1, Mar. 31, 2022
Int. Cl. A61B 8/08 (2006.01); A61B 8/04 (2006.01); A61B 8/14 (2006.01); G06T 7/11 (2017.01); G06T 7/20 (2017.01); G06T 7/30 (2017.01)
CPC A61B 8/0891 (2013.01) [A61B 8/04 (2013.01); A61B 8/145 (2013.01); G06T 7/11 (2017.01); G06T 7/20 (2013.01); G06T 7/30 (2017.01); G06T 2207/10136 (2013.01); G06T 2207/30101 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for generating a non-invasive measure of blood vessel rigidity for a subject, the method comprising:
obtaining 2D ultrasound data of a blood vessel acquired from a first measurement location, wherein the 2D ultrasound data provides information relating to a movement of the blood vessel;
obtaining 3D ultrasound data of the blood vessel acquired from the first measurement location, wherein the 3D ultrasound data provides information relating to a 3D geometry of the blood vessel, wherein the 2D ultrasound data and 3D ultrasound data are obtained from two separate ultrasound data acquisitions performed at said first measurement location;
determining a motion of the blood vessel based on the movement of the blood vessel from the 2D ultrasound data;
obtaining a non-invasive pressure measurement from the subject;
providing the determined motion of the blood vessel, the 3D geometry of the blood vessel and the non-invasive pressure measurement to a biomechanical model; and
generating a measure of rigidity of the blood vessel based on the biomechanical model.