US 12,320,795 B2
Measurement systems and associated techniques for sensing electrical characteristics of a sensor
Sergey A. Dryga, Rio Rancho, NM (US); and Jonathon D. McMillan, Tijeras, NM (US)
Assigned to NanoDX, Inc., Southborough, MA (US)
Filed by NanoDX, Inc., Southborough, MA (US)
Filed on Mar. 16, 2021, as Appl. No. 17/203,425.
Claims priority of provisional application 62/991,515, filed on Mar. 18, 2020.
Prior Publication US 2021/0293776 A1, Sep. 23, 2021
Int. Cl. G01N 33/48 (2006.01); G01N 27/414 (2006.01); G01N 27/60 (2006.01); G01N 33/487 (2006.01); G01R 27/14 (2006.01)
CPC G01N 33/48707 (2013.01) [G01N 27/4146 (2013.01); G01N 27/60 (2013.01); G01R 27/14 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A system comprising:
a sensor configured to generate an impedance greater than 0.5 megaohms (M Ω) when at least some analytes are disposed proximate the sensor; and
circuitry configured to provide an alternating current (AC) voltage to the sensor and sense electrical characteristics of the sensor in response to the AC voltage, the circuitry comprising:
a sense resistor coupled to the sensor;
a first amplifier having a first input, a second input, and an output, with the sense resistor coupled between the second input and the output; and
a second amplifier comprising:
a first input coupled to the output of the first amplifier;
a second input coupled to the first input of the first amplifier; and
an output configured to provide a voltage indicative of the electrical characteristics of the sensor,
wherein the first amplifier is configured to provide the AC voltage to the sensor via the second input.