US 12,319,954 B2
Morphinan compounds
Roger Tung, Lexington, MA (US)
Assigned to Concert Pharmaceuticals, Inc., Lexington, MA (US)
Filed by Concert Pharmaceuticals, Inc., Lexington, MA (US)
Filed on Apr. 25, 2023, as Appl. No. 18/306,710.
Application 18/306,710 is a continuation of application No. 17/942,555, filed on Sep. 12, 2022.
Application 17/942,555 is a continuation of application No. 17/120,880, filed on Dec. 14, 2020, granted, now 11,473,123, issued on Oct. 18, 2022.
Application 17/120,880 is a continuation of application No. 15/839,387, filed on Dec. 12, 2017, abandoned.
Application 15/839,387 is a continuation of application No. 15/068,404, filed on Mar. 11, 2016, granted, now 9,868,976, issued on Jan. 16, 2018.
Application 15/068,404 is a continuation of application No. 14/334,227, filed on Jul. 17, 2014, granted, now 9,314,440, issued on Apr. 19, 2016.
Application 14/334,227 is a continuation of application No. 14/141,694, filed on Dec. 27, 2013, granted, now 9,072,711, issued on Jul. 7, 2015.
Application 14/141,694 is a continuation of application No. 13/949,499, filed on Jul. 24, 2013, granted, now 8,748,450, issued on Jun. 10, 2014.
Application 13/949,499 is a continuation of application No. 13/118,935, filed on May 31, 2011, granted, now 8,541,436, issued on Sep. 24, 2013.
Application 13/118,935 is a continuation of application No. 12/112,936, filed on Apr. 30, 2008, granted, now 7,973,049, issued on Jul. 5, 2011.
Claims priority of provisional application 60/976,044, filed on Sep. 28, 2007.
Claims priority of provisional application 60/916,662, filed on May 8, 2007.
Claims priority of provisional application 60/915,130, filed on May 1, 2007.
Prior Publication US 2024/0117407 A1, Apr. 11, 2024
Int. Cl. C07D 221/28 (2006.01); A61K 31/195 (2006.01); A61K 31/439 (2006.01); A61K 31/4709 (2006.01); A61K 31/485 (2006.01); A61K 31/49 (2006.01); C07B 59/00 (2006.01); C07D 471/08 (2006.01); C12Q 1/28 (2006.01); G01N 33/49 (2006.01); G01N 33/493 (2006.01)
CPC C12Q 1/28 (2013.01) [A61K 31/195 (2013.01); A61K 31/4709 (2013.01); A61K 31/485 (2013.01); A61K 31/49 (2013.01); C07B 59/002 (2013.01); C07D 221/28 (2013.01); C07D 471/08 (2013.01); G01N 33/491 (2013.01); G01N 33/493 (2013.01)] 17 Claims
 
1. A compound having the formula:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.