	US 12,319,912 B2
	MicroRNA expression promoting agent and food or beverage for promoting expression of microRNA
Kurataka Otsuka, Chofu (JP); and Takahiro Ochiya, Tokyo (JP)
Assigned to Kewpie Corporation, Tokyo (JP)
Appl. No. 17/436,721
Filed by Kewpie Corporation, Tokyo (JP)
PCT Filed Mar. 5, 2020, PCT No. PCT/JP2020/009481 § 371(c)(1), (2) Date Sep. 7, 2021, PCT Pub. No. WO2020/184390, PCT Pub. Date Sep. 17, 2020.
Claims priority of application No. 2019-042523 (JP), filed on Mar. 8, 2019.
Prior Publication US 2022/0170014 A1, Jun. 2, 2022
Int. Cl. A23L 33/13 (2016.01); A61K 31/712 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2018.01)

CPC C12N 15/113 (2013.01) [A23L 33/13 (2016.08); A61K 31/712 (2013.01)]

11 Claims

1. A method for promoting the expression of a microRNA, comprising:

administering pterostilbene to a subject in need thereof,

wherein the microRNA is at least one selected from the group consisting of miR-34a, miR-16, miR-126, miR-193b, and let-7a,

wherein the pterostilbene is administered in an amount effective to increase the expression level of the microRNA from a state in which the expression level of the microRNA has been lowered to an expression level of a healthy subject.