US 12,319,707 B2
Dosage unit form(s) comprising BTS and BTS(OMe) for use in boron neutron capture therapy and methods thereof
Michael Y. Torgov, Redondo Beach, CA (US); and Tioga J. Martin, Los Angeles, CA (US)
Assigned to TAE Life Sciences, LLC, Irvine, CA (US)
Filed by TAE Life Sciences, Irvine, CA (US)
Filed on Nov. 15, 2023, as Appl. No. 18/445,603.
Application 18/445,603 is a continuation of application No. 17/803,487, filed on Aug. 1, 2022, granted, now 11,884,688.
Claims priority of provisional application 63/259,662, filed on Jul. 30, 2021.
Prior Publication US 2024/0092808 A1, Mar. 21, 2024
Int. Cl. C07F 5/02 (2006.01)
CPC C07F 5/025 (2013.01) 11 Claims
 
1. A method of delivering a borylated amino acid composition to cell for the treatment of disease comprising:
(i) administering to a patient a Dosage Unit Form comprising a composition having a chemical structure as follows:

OG Complex Work Unit Chemistry
(ii) accumulating the Dosage Unit Form into a cell; and
(iii) irradiating the cell with neutrons.