US 12,319,567 B2
GHz-THz ultrasonics and optics for neurotechnology devices, methods, and applications
Amit Lal, Ithaca, NY (US); Chris Xu, Ithaca, NY (US); and Ankur Singh, Ithaca, NY (US)
Assigned to CORNELL UNIVERSITY, Ithaca, NY (US)
Appl. No. 17/058,237
Filed by CORNELL UNIVERSITY, Ithaca, NY (US)
PCT Filed May 23, 2019, PCT No. PCT/US2019/033688
§ 371(c)(1), (2) Date Nov. 24, 2020,
PCT Pub. No. WO2019/226862, PCT Pub. Date Nov. 28, 2019.
Claims priority of provisional application 62/675,973, filed on May 24, 2018.
Prior Publication US 2021/0187329 A1, Jun. 24, 2021
Int. Cl. A61N 7/00 (2006.01); B06B 1/06 (2006.01); B81C 1/00 (2006.01); H10N 30/853 (2023.01); H10N 39/00 (2023.01); A61B 5/00 (2006.01)
CPC B81C 1/00238 (2013.01) [A61N 7/00 (2013.01); B06B 1/0622 (2013.01); H10N 30/853 (2023.02); H10N 39/00 (2023.02); A61B 5/0084 (2013.01); A61N 2007/0026 (2013.01); A61N 2007/0047 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A neuro-cognitive system, comprising:
an implantable device, the implantable device including:
a substrate having a first surface and a second surface opposite the first surface;
a cellular interaction region disposed at or in the first surface of the substrate;
an electrode electrically connected to the cellular interaction region; and
a CMOS chip, comprising a plurality of transducers, attached to the second surface of the substrate wherein the plurality of transducers comprise a first plurality of transducers configured to transmit phased ultrasonic beams through the substrate toward the cellular interaction region to interrogate, to impart energy to, or to activate, in vivo, one or more cells or one or more biological structures at or adjacent the cellular interaction region and wherein the plurality of transducers further comprise a second plurality of transducers configured to receive return signals from the one or more cells or one or more biological structures at or adjacent the cellular interaction region responsive to the transmitted phased ultrasonic beams.