| CPC A61N 5/1037 (2013.01) [A61N 5/1049 (2013.01); A61N 5/1068 (2013.01); G16H 40/60 (2018.01); A61N 2005/1058 (2013.01); A61N 2005/1061 (2013.01); A61N 2005/1087 (2013.01); A61N 2005/1097 (2013.01)] | 20 Claims |

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1. A system for use with a radiation therapy system that generates a charged particle beam to ablate targeted tissue of a heart of a patient for non-invasive treatment of heart arrhythmia, the system comprising:
an ultrasound cardiac imaging system configured to image a region of the heart to assess motion of the targeted tissue and corresponding cardiac and respiratory cycle phases of the patient; and
a control system configured to process an irradiation plan comprising positional information of the targeted tissue imaged during a planning stage, the control system further configured to, during a treatment stage, process ultrasound images acquired with the ultrasound cardiac imaging system and instruct the radiation therapy system to generate the charged particle beam in accordance with the irradiation plan to ablate the targeted tissue of the heart based on information of the cardiac and respiratory cycle phases provided by the ultrasound cardiac imaging system during the treatment stage.
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