| CPC A61M 1/34 (2013.01) [A61M 1/1621 (2014.02); A61M 1/1631 (2014.02); A61M 5/165 (2013.01); B01D 63/082 (2013.01); B01D 63/085 (2013.01); A61M 1/1678 (2013.01); A61M 2205/04 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/75 (2013.01); A61M 2206/10 (2013.01); A61M 2206/11 (2013.01); B01D 2313/105 (2013.01); B01D 2313/125 (2013.01); F28F 2009/029 (2013.01)] | 17 Claims |

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1. A hemofilter for use in filtering blood in vivo, the hemofilter comprising:
a housing comprising an inlet and an outlet;
an inlet conduit connected to the inlet, wherein the inlet conduit comprises a circular cross section geometry at a first region proximal to the inlet and transitioning into a rectangular cross section geometry at a second region distal to the first region, and a curved region having a rectangular cross section geometry connected to the second distal region;
a single serpentine filtration channel connected to the curved region comprising a plurality of filtration sections arranged in a spaced-apart stacked configuration wherein the plurality of filtration sections are connected via turnaround sections; and
an outlet conduit connected to the outlet, wherein the outlet conduit comprises a rectangular cross-section geometry at a first region distal to the outlet and transitioning into a circular cross section geometry at a second region proximal to the outlet.
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