	US 12,318,404 B2
	Hypochlorite formulations for wound healing
Andrew Hoover, Pleasant Grove, UT (US); and Kurt Richards, Herriman, UT (US)
Assigned to Reoxcyn LLC, Ogden, UT (US)
Filed by Reoxcyn, LLC, Ogden, UT (US)
Filed on Jan. 18, 2017, as Appl. No. 15/409,379.
Claims priority of provisional application 62/280,613, filed on Jan. 19, 2016.
Prior Publication US 2017/0202877 A1, Jul. 20, 2017
Int. Cl. A61K 33/20 (2006.01); A61K 8/19 (2006.01); A61K 8/24 (2006.01); A61K 8/25 (2006.01); A61K 8/891 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 45/06 (2006.01); A61K 47/02 (2006.01); A61K 47/24 (2006.01); A61K 47/34 (2017.01); A61L 26/00 (2006.01); A61Q 19/08 (2006.01); C25B 1/26 (2006.01)

CPC A61K 33/20 (2013.01) [A61K 8/19 (2013.01); A61K 8/24 (2013.01); A61K 8/25 (2013.01); A61K 8/891 (2013.01); A61K 9/0014 (2013.01); A61K 9/08 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/24 (2013.01); A61K 47/34 (2013.01); A61L 26/0004 (2013.01); A61Q 19/08 (2013.01); C25B 1/26 (2013.01); A61K 2800/81 (2013.01)]

20 Claims

1. A method of treating a burn in a subject afflicted with a burn, the method comprising:

applying to a burn a therapeutically effective amount of a formulation consisting of:

an electrolyzed saline solution having a salt concentration between 0.1% and 1% by weight, hypochlorite present in an amount of between 0.6 and 1% w/v, hypochlorous acid, dissolved oxygen, chlorine, hydrogen gas, hydrogen peroxide, hydrogen ions, hypochloride, ozone, activated hydrogen ions, chloride ions, hydroxides, singlet oxygen, *OCl, *HO⁻, and superoxides of *O₂— and HO₂;

a buffer, wherein the formulation has a pH ranging from 6.7 to 7.5;

sodium magnesium silicate; and

dimethicone,

wherein the formulation has an osmolality measurement ranging from about 22 mOsm/kg to about 54 mOsm/kg; and

allowing the formulation to absorb into the burn, thereby treating the burn.