CPC H01J 49/0036 (2013.01) [H01J 49/025 (2013.01); H01J 49/406 (2013.01)] | 20 Claims |
1. A method of gain calibration for an ion detector operating at a detector voltage, the method comprising steps of:
generating single ions;
determining a parameter of a first relationship between a detector output of an ion detector and a number of ions for a first detector voltage, by detecting single ions at the ion detector;
detecting an ion peak at the ion detector using the first detector voltage, to determine a number of ions in the ion peak, based on the parameter of the first relationship;
adjusting the detector voltage to reduce a ratio between the detector output and a noise level and thereby obtain a second detector voltage at which the detector output for the ion peak remains above the noise level;
determining a parameter of a second relationship between the detector output and the number of ions for the second detector voltage, based on the determined number of ions in the ion peak.
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