US 11,994,509 B2
Collecting components of a fluid
Marlene Bainbridge, Golden, CO (US); Todd Curtis Green, Lakewood, CO (US); and Logan Fender, Lakewood, CO (US)
Assigned to Terumo BCT, Inc., Lakewood, CO (US)
Filed by Terumo BCT, Inc., Lakewood, CO (US)
Filed on May 16, 2022, as Appl. No. 17/745,352.
Application 16/812,582 is a division of application No. 15/783,866, filed on Oct. 13, 2017, granted, now 10,585,085, issued on Mar. 10, 2020.
Application 17/745,352 is a continuation of application No. 16/812,582, filed on Mar. 9, 2020, granted, now 11,366,096.
Claims priority of provisional application 62/407,607, filed on Oct. 13, 2016.
Prior Publication US 2022/0276220 A1, Sep. 1, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 1/36 (2006.01); B01D 21/24 (2006.01); B01D 21/26 (2006.01); B01D 21/34 (2006.01); B04B 5/04 (2006.01); G01N 33/49 (2006.01)
CPC G01N 33/491 (2013.01) [A61M 1/3693 (2013.01); A61M 1/3696 (2014.02); B01D 21/2472 (2013.01); B01D 21/262 (2013.01); B01D 21/34 (2013.01); B04B 5/0442 (2013.01); A61M 1/362227 (2022.05); A61M 1/36225 (2022.05); A61M 2202/0021 (2013.01); A61M 2202/0427 (2013.01); A61M 2202/0439 (2013.01); A61M 2205/3334 (2013.01); B01D 2221/10 (2013.01); B04B 2005/0471 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method, comprising:
receiving, by at least one processor, either a first indication of a first collection procedure for collecting a first product from whole blood or a second indication of a second collection procedure for collecting a concentrated product from the whole blood;
when the at least one processor receives the first indication:
receiving, by the at least one processor, first data related to a first amount of a first component in the whole blood from a first source;
rotating a centrifuge at a first centrifuge speed;
introducing the whole blood from the first source into a first separation vessel on the centrifuge at a first flow rate to separate a first composite fluid from the whole blood from the first source;
introducing the first composite fluid, separated from the whole blood from the first source, into a first separation chamber at a first chamber flow rate;
separating the first composite fluid into at least the first component and a second component by subjecting the first composite fluid while in the first separation chamber to a first centrifugal field created by the centrifuge rotating at the first centrifuge speed;
during the separating, maintaining an amount of at least one of the first component of the first composite fluid and the second component of the first composite fluid in the first separation chamber below a predetermined amount;
determining a depletion in the amount of the first component in the whole blood from the first source;
changing, in response to determining the depletion in the amount of the first component in the whole blood from the first source, the first flow rate to introduce the whole blood from the first source into the first separation vessel at a second flow rate; and
collecting the first component of the first composite fluid in a first storage container to form the first product; and
when the at least one processor receives the second indication:
receiving, by the at least one processor, the first data;
determining, by the at least one processor, a second chamber flow rate based on the first data;
determining a second centrifuge speed based on the second chamber flow rate;
rotating the centrifuge at the second centrifuge speed;
introducing the whole blood from the first source into the first separation vessel at a third flow rate to separate a second composite fluid from the whole blood from the first source;
introducing the second composite fluid, separated from the whole blood from the first source, into the first separation chamber at the second chamber flow rate;
separating the second composite fluid into at least the first component and the second component by subjecting the second composite fluid while in the first separation chamber to a second centrifugal field created by the centrifuge rotating at the second centrifuge speed; and
collecting the first component of the second composite fluid in the first storage container to form the concentrated product.