US 11,993,609 B2
Compositions and methods for oral delivery of crystalline PRX-3140 potassium salt
James David Talton, Alachua, FL (US); Mianji Zhang, Alachua, FL (US); Lianhao Zhang, Alachua, FL (US); Otto Joseph Geoffroy, Alachua, FL (US); and Daniel Gerard Morgan, Alachua, FL (US)
Assigned to Nanopharmaceutics, Inc., Alachua, FL (US)
Filed by Nanopharmaceutics, Inc., Alachua, FL (US)
Filed on May 10, 2023, as Appl. No. 18/195,506.
Application 18/195,506 is a continuation of application No. 17/830,519, filed on Jun. 2, 2022, granted, now 11,725,016.
Prior Publication US 2023/0391791 A1, Dec. 7, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 495/04 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); C07D 497/04 (2006.01)
CPC C07D 495/04 (2013.01) [A61K 9/0053 (2013.01); A61K 9/1682 (2013.01); C07D 497/04 (2013.01); C07B 2200/13 (2013.01)] 28 Claims
 
1. A composition comprising a compound of Formula I:

OG Complex Work Unit Chemistry
wherein the compound of Formula I comprises a crystalline form of the compound of Formula I and wherein the composition further comprises:
(a) a compound of Formula II:

OG Complex Work Unit Chemistry
and/or
(b) a compound of Formula III:

OG Complex Work Unit Chemistry