US 11,992,833 B2
Pipette tip extension for treating a sample with a liquid attachable to a pipette tip
Adrian Sager, Mannedorf (CH); Philipp Ott, Steg (CH); Patrick Kinney, Hayward, CA (US); Hagen Reinhardt, Bolligen (CH); Michael Keller, Bauma (CH); and Sujata Iyer, San Jose, CA (US)
Assigned to TECAN TRADING AG, Mannedorf (CH)
Appl. No. 17/295,624
Filed by TECAN TRADING AG, Mannedorf (CH)
PCT Filed Dec. 20, 2019, PCT No. PCT/US2019/067755
§ 371(c)(1), (2) Date May 20, 2021,
PCT Pub. No. WO2020/132394, PCT Pub. Date Jun. 25, 2020.
Claims priority of application No. PCT/US2018/066850 (WO), filed on Dec. 20, 2018; and application No. PCT/US2018/066857 (WO), filed on Dec. 20, 2018.
Prior Publication US 2022/0023854 A1, Jan. 27, 2022
Int. Cl. G01N 35/10 (2006.01); B01L 3/00 (2006.01); B01L 3/02 (2006.01); B03C 1/01 (2006.01); B03C 1/32 (2006.01)
CPC B01L 3/0275 (2013.01) [B01L 3/0279 (2013.01); B03C 1/01 (2013.01); B03C 1/32 (2013.01); G01N 35/10 (2013.01); B01L 3/0217 (2013.01); B01L 2200/023 (2013.01); B01L 2200/025 (2013.01); B01L 2200/026 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/18 (2013.01); B01L 2400/0478 (2013.01); G01N 2035/103 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A pipette tip extension attachable to a pipette tip, the pipette tip extension comprising:
a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end, the exterior wall having an outer side and an inner side and forming at the proximal end a reception aperture for inserting the pipette tip, and at the distal end a dispense aperture,
an inner cavity enclosed by the inner side of the exterior wall,
a distance element connected to the inner side of the exterior wall, the distance element being configured to position the pipette tip within the inner cavity and to establish a fluid uptake area adjacent to the inner side of the exterior wall, the fluid uptake area extending from the dispense aperture towards the reception aperture and being in fluid connection with the surrounding atmosphere at the reception aperture, and
a constriction element which is connected to the inner side of the exterior wall of the pipette tip extension, the constriction element being configured to control an insertion depth of a pipette tip within the pipette tip extension and thereby to define a gap with a gap height (h) between a distal end of an inserted pipette tip and the distal end of the pipette tip extension, the constriction element defining an end stop for a pipette tip and is configured as a fluid-permeable sieve-like structure.