US 11,992,686 B2
Flexible spinal cord stimulators for pain and trauma management through neuromodulation
Bilwaj Gaonkar, Los Angeles, CA (US); Steven L. Moran, Los Angeles, CA (US); Amir Hanna, Los Angeles, CA (US); Luke Macyszyn, Los Angeles, CA (US); and Subramanian S. Iyer, Los Angeles, CA (US)
Assigned to The Regents of the University of California, Oakand, CA (US)
Appl. No. 16/981,204
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
PCT Filed Mar. 15, 2019, PCT No. PCT/US2019/022524
§ 371(c)(1), (2) Date Sep. 15, 2020,
PCT Pub. No. WO2019/178507, PCT Pub. Date Sep. 19, 2019.
Claims priority of provisional application 62/644,284, filed on Mar. 16, 2018.
Prior Publication US 2020/0406039 A1, Dec. 31, 2020
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01); A61N 1/378 (2006.01)
CPC A61N 1/36139 (2013.01) [A61N 1/0551 (2013.01); A61N 1/36062 (2017.08); A61N 1/378 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A spinal cord stimulator comprising:
a flexible substrate comprised of a flexible material that is configured to have a Young's modulus of less than 3 MPa, the flexible substrate forming a contiguous structure housing all of:
a power source embedded in the flexible substrate;
a controller embedded in the flexible substrate and connected to the power source; and
an array of electrodes, including an array of stimulation electrodes and an array of sensing electrodes, disposed on a surface of the flexible substrate and connected to the controller,
wherein the controller is configured to direct the array of stimulation electrodes on the surface of the flexible substrate to deliver a stimulation pattern to a spinal cord of a patient, and
wherein the controller is configured to perform machine learning, responsive to the signals received from the array of sensing electrodes, to determine a set of stimulation parameters, and
wherein the controller is configured to adjust the stimulation pattern according to the set of stimulation parameters, and
wherein the controller includes a neuromorphic computing component.