US 11,992,515 B2
Method for treating pulmonary fibrosis using S100A3 protein
Eid Abdullah Al Mutairy, Riyadh (SA); Mohammed Khalid, Riyadh (SA); and Futwan Al-Mohanna, Riyadh (SA)
Assigned to KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE, Riyadh (SA)
Filed by KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE, Riyadh (SA)
Filed on Oct. 26, 2020, as Appl. No. 17/080,268.
Application 17/080,268 is a continuation of application No. 16/155,371, filed on Oct. 9, 2018, abandoned.
Prior Publication US 2021/0052700 A1, Feb. 25, 2021
Int. Cl. A61P 11/00 (2006.01); A61K 9/00 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61P 9/04 (2006.01); A61P 11/08 (2006.01); C07K 14/47 (2006.01); C12N 15/52 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6813 (2018.01); C12Q 1/6827 (2018.01)
CPC A61K 38/1738 (2013.01) [A61P 9/04 (2018.01); A61P 11/00 (2018.01); C07K 14/4728 (2013.01); C12N 15/52 (2013.01); A61K 9/0073 (2013.01); A61K 9/0075 (2013.01); C12Q 1/6813 (2013.01); C12Q 1/6827 (2013.01)] 7 Claims
 
1. A method for treating pulmonary fibrosis in a subject carrying missense variant rs13835706 comprising detecting a mutant S100A3 polynucleotide comprising SEQ ID NO: 3 in a biological sample from the subject and administering a therapeutic agent treating the subject for pulmonary fibrosis.