| CPC G05D 7/0652 (2013.01) [A61M 1/1524 (2022.05); A61M 1/154 (2022.05); A61M 1/155 (2022.05); A61M 1/1561 (2022.05); A61M 1/1565 (2022.05); A61M 1/1656 (2013.01); A61M 1/166 (2014.02); A61M 1/267 (2014.02); A61M 1/3644 (2014.02); F16K 11/20 (2013.01); F16K 31/046 (2013.01); A61M 1/159 (2022.05); A61M 2205/128 (2013.01); A61M 2205/3303 (2013.01); A61M 2205/3317 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/505 (2013.01)] | 26 Claims |

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1. A dialysis machine, comprising:
a housing; and
a drive unit located at least partially within the housing, the drive unit comprising an actuator configured to engage and move a plurality of valves disposed within a fluid cassette to selectively open and close each valve of the plurality of valves; and
a positioning frame located within the housing, the positioning frame disposed adjacent the fluid cassette and along which the drive unit can be moved in three dimensions to align the actuator with a selected valve of the plurality of valves.
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