US 12,312,357 B2
PRMT5 inhibiting compounds and uses thereof
Ming Zhang, Shanghai (CN); Ya Kong, Shanghai (CN); Lulu Jiang, Shanghai (CN); Bin Jiang, Shanghai (CN); Guoqiang Dai, Shanghai (CN); Yulong He, Shanghai (CN); Bing Hou, Shanghai (CN); Bo Shan, Shanghai (CN); and Jay Mei, Shanghai (CN)
Assigned to ANTENGENE DISCOVERY LIMITED, Shanghai (CN)
Filed by ANTENGENE DISCOVERY LIMITED, Shanghai (CN)
Filed on Feb. 28, 2024, as Appl. No. 18/589,461.
Application 18/589,461 is a continuation of application No. PCT/CN2024/072763, filed on Jan. 17, 2024.
Claims priority of application No. PCT/CN2023/072921 (WO), filed on Jan. 18, 2023; application No. PCT/CN2023/093297 (WO), filed on May 10, 2023; and application No. PCT/CN2024/071750 (WO), filed on Jan. 11, 2024.
Prior Publication US 2024/0262835 A1, Aug. 8, 2024
Int. Cl. C07D 487/04 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); C07D 471/14 (2006.01); C07D 519/00 (2006.01)
CPC C07D 487/04 (2013.01) [A61K 31/4985 (2013.01); A61K 31/506 (2013.01); C07D 471/14 (2013.01); C07D 519/00 (2013.01)] 3 Claims
 
1. A compound having a structure of:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.