US 12,311,355 B2
Modular sample preparation devices and methods
Anna K. Boardman, Watertown, MA (US); Xiaoxiao Liu, Natick, MA (US); Micah Watt, Quincy, MA (US); Jonathan Belanger, Whitinsville, MA (US); Matthew A. Lauber, North Smithfield, RI (US); Michael Lavallee, Whitinsville, MA (US); and Wenhao Zhu, Natick, MA (US)
Assigned to Waters Technologies Corporation, Milford, MA (US)
Filed by Waters Technologies Corporation, Milford, MA (US)
Filed on Feb. 3, 2021, as Appl. No. 17/166,051.
Claims priority of provisional application 62/970,935, filed on Feb. 6, 2020.
Prior Publication US 2021/0245150 A1, Aug. 12, 2021
Int. Cl. B01L 3/00 (2006.01); B01L 3/02 (2006.01)
CPC B01L 3/502 (2013.01) [B01L 3/0275 (2013.01); B01L 2200/028 (2013.01); B01L 2200/12 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A method of producing a liquid sample preparation device, the method comprising:
selecting a modular reservoir portion based on a desired liquid manipulator interface design, the modular reservoir portion having a first end having a liquid manipulator interface portion and a second end opposing the first end;
selecting a modular body portion based on a desired sample preparation receptacle characteristic, wherein the modular body portion comprises a resin disposed within the modular body;
selecting a modular tip portion based on desired outlet droplet shape or to minimize internal surface area, the tip portion having an inlet and an outlet at an end opposing the inlet; and
fluidly connecting the second end of the modular reservoir portion to a first end of the modular body portion and fluidly connecting a second end of the modular body portion to the inlet of the modular tip portion to create a flow path.