US 12,310,980 B2
Synthesis of a potent aromatase inhibitor 17α-acetoxy-10β,11β-dihydroxy-progesterone for the treatment of ER+ breast cancer
Muhammad Iqbal Choudhary, Karachi (PK); Atia-tul- Wahab, Karachi (PK); Humaira Zafar, Karachi (PK); Ambreen Aziz, Karachi (PK); Nimra Naveed Shaikh, Karachi (PK); and Atta-ur- Rahman, Karachi (PK)
Filed by Muhammad Iqbal Choudhary, Karachi (PK); Atia-tul- Wahab, Karachi (PK); Humaira Zafar, Karachi (PK); Ambreen Aziz, Karachi (PK); Nimra Naveed Shaikh, Karachi (PK); and Atta-ur- Rahman, Karachi (PK)
Filed on Mar. 30, 2023, as Appl. No. 18/128,246.
Prior Publication US 2023/0241079 A1, Aug. 3, 2023
Int. Cl. A61K 31/57 (2006.01); A61P 35/00 (2006.01)
CPC A61K 31/57 (2013.01) [A61P 35/00 (2018.01)] 2 Claims
 
1. A gestonorone acetate derivative, 17α-acetoxy-10β,11β-dihydroxy-progesterone, having the following chemical structure:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.