US 12,310,922 B2
System and method for making personalized individual unit doses containing pharmaceutical actives
Alexander Mark Schobel, Warren, NJ (US); Keith Kendall, Warren, NJ (US); Dan Barber, Warren, NJ (US); Theresa Wood, Warren, NJ (US); Peter Boyd, Warren, NJ (US); and John Maxwell, Warren, NJ (US)
Assigned to Aquestive Therapeutics, Inc., Warren, NJ (US)
Filed by Aquestive Therapeutics, Inc., Warren, NJ (US)
Filed on Sep. 7, 2023, as Appl. No. 18/243,211.
Application 18/243,211 is a division of application No. 16/447,107, filed on Jun. 20, 2019, granted, now 11,806,311.
Claims priority of provisional application 62/729,051, filed on Sep. 10, 2018.
Claims priority of provisional application 62/700,444, filed on Jul. 19, 2018.
Claims priority of provisional application 62/688,107, filed on Jun. 21, 2018.
Prior Publication US 2023/0414452 A1, Dec. 28, 2023
Int. Cl. A61K 9/00 (2006.01); A61J 3/00 (2006.01); G16H 20/13 (2018.01); G16H 20/17 (2018.01)
CPC A61J 3/00 (2013.01) [G16H 20/13 (2018.01); G16H 20/17 (2018.01); A61J 2200/70 (2013.01); A61J 2205/10 (2013.01); A61J 2205/20 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method for creating one or more personalized individual unit doses (IUDs) containing a prescribed amount of active for distribution and administration to an individual, the method comprising:
providing a medical professional with personal health information of the individual;
prescribing by the medical professional, a medical prescription comprising an amount of active to be administered to the individual as determined, at least in part, on the personal health information, the medical prescription comprising a treatment regimen for administering a prescribed amount of the active per personalized individual unit dose (IUD);
electronically communicating at least a part of the medical prescription to a manufacturer of IUDs;
manufacturing the IUD using one or more apparatus for making personalized IUDs; and
distributing the IUDs to the individual;
wherein manufacturing the IUD includes one or more of the following steps:
providing carrier matrix selected from the group consisting of polyethylene oxide, polyvinyl pyrrolidone, polyvinyl alcohol, cellulosic polymers, polysaccharides, gums, and combinations thereof to one or more of the apparatus;
providing the active to the one or more of the apparatus;
combining the active and carrier matrix in the one or more of the apparatus comprising a mixing and film forming process or a matrix depositing assembly; and
forming the carrier matrix and the active into a film.