| CPC A61B 5/14546 (2013.01) [A61B 5/0002 (2013.01); A61B 5/6801 (2013.01); H03H 7/00 (2013.01); H03M 1/66 (2013.01); A61B 2562/06 (2013.01)] | 20 Claims |

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1. A wearable device comprising:
an analog multiplexer, the analog multiplexer comprising:
a plurality of impedance circuit elements, each of the plurality of impedance circuit elements comprising a source pin and a sink pin, wherein the sink pin of at least a first one of the plurality of impedance circuit elements is coupled to the source pin of a second one of the plurality of impedance circuit elements; and
a circuit element to generate N selection signals for selecting a signal to be output from the analog multiplexer; and
an analog front end (AFE) to resolve input and output conditions for selecting an output from the analog multiplexer, wherein:
each impedance circuit element in the plurality of impedance circuit elements comprises a sensor configured to detect at least one analyte,
each sensor includes:
at least a first electrode conductively coupled to a first contact pad and a second electrode conductively coupled to a second contact pad, the first contact pad coupled to the source pin of the impedance circuit element and the second contact pad coupled to the sink pin of the impedance circuit element;
semiconducting nanostructures on at least one in the plurality of electrodes; and
a type of capture reagent attached to the semiconducting nanostructures, the type of capture reagent to bind to the at least one analyte, and
different sensors have correspondingly different types of capture reagents to bind to different analytes.
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