US 11,988,665 B2
Systems and methods for determining viruses such as coronaviruses
Arnon Chait, Bay Village, OH (US); and Boris Y. Zaslavsky, Solon, OH (US)
Assigned to Analiza, Inc., Cleveland, OH (US)
Appl. No. 17/800,296
Filed by Analiza, Inc., Cleveland, OH (US)
PCT Filed Feb. 26, 2021, PCT No. PCT/US2021/019795
§ 371(c)(1), (2) Date Aug. 17, 2022,
PCT Pub. No. WO2021/173915, PCT Pub. Date Sep. 2, 2021.
Claims priority of provisional application 63/091,849, filed on Oct. 14, 2020.
Claims priority of provisional application 63/071,472, filed on Aug. 28, 2020.
Claims priority of provisional application 63/003,843, filed on Apr. 1, 2020.
Claims priority of provisional application 63/000,441, filed on Mar. 26, 2020.
Claims priority of provisional application 62/987,385, filed on Mar. 10, 2020.
Claims priority of provisional application 62/982,880, filed on Feb. 28, 2020.
Prior Publication US 2023/0088162 A1, Mar. 23, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/569 (2006.01); C12Q 1/6888 (2018.01); C12Q 1/70 (2006.01); G01N 33/49 (2006.01)
CPC G01N 33/56983 (2013.01) [C12Q 1/6888 (2013.01); C12Q 1/70 (2013.01); G01N 33/491 (2013.01); G01N 2333/11 (2013.01); G01N 2333/165 (2013.01)] 20 Claims
 
1. A method, comprising:
partitioning a biological fluid in an aqueous multi-phase partitioning system, wherein the biological fluid arises from a subject suspected of being infected with a virus, and wherein the aqueous multi-phase partitioning system comprises two or more immiscible aqueous phases; and
determining the virus in at least one phase of the partitioning system using an agent comprising a signaling moiety and a virus-binding moiety.