US 11,988,659 B2
Nanopore arrays
Roger J. A. Chen, Saratoga, CA (US); and David J. Fullagar, Los Gatos, CA (US)
Assigned to Roche Sequencing Solutions, Inc., Pleasanton, CA (US)
Filed by Roche Sequencing Solutions, Inc., Pleasanton, CA (US)
Filed on Sep. 15, 2020, as Appl. No. 16/948,372.
Application 16/948,372 is a continuation of application No. 15/983,426, filed on May 18, 2018, granted, now 10,809,244.
Application 15/983,426 is a continuation of application No. 15/462,483, filed on Mar. 17, 2017, granted, now 10,012,637, issued on Jul. 3, 2018.
Application 15/462,483 is a continuation of application No. 13/759,701, filed on Feb. 5, 2013, granted, now 9,759,711, issued on Sep. 12, 2017.
Prior Publication US 2020/0408736 A1, Dec. 31, 2020
Int. Cl. G01N 33/487 (2006.01); G11C 7/00 (2006.01); G11C 16/34 (2006.01)
CPC G01N 33/48721 (2013.01) [G11C 7/00 (2013.01); G11C 16/34 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A system for analyzing a plurality of molecules, the system comprising:
a nanopore array including a plurality of cells included on a chip;
a fluidic system configured to send one or more reagents to the nanopore array;
a data interface configured to receive measurements from the plurality of cells; and
a master controller, the master controller programmed to:
assemble lipid bilayers in the plurality of cells;
insert nanopores into the assembled lipid bilayers;
determine states of the plurality of cells based on measurements from the plurality of cells;
analyze a sample using the inserted nanopores;
after analyzing the sample; direct the fluidic system to rinse out the contents within the cells;
assemble new lipid bilayers in the plurality of cells;
insert nanopores into the new lipid bilayers;
determine states of the plurality of cells with the new lipid bilayers based on measurements from the plurality of cells; and
analyze a second sample using the nanopores inserted into the new lipid bilayers.