US 11,987,789 B2
Systems, devices, and methods for isotachophoresis
Lewis A. Marshall, Oakland, CA (US); Amy L. Hiddessen, Pleasanton, CA (US); Nathan P. Hoverter, Pleasanton, CA (US); Klint A. Rose, Oakland, CA (US); Juan G. Santiago, Stanford, CA (US); Matthew S. Munson, Evanston, IL (US); Janine Mok, Palo Alto, CA (US); Sean Arin, Oakland, CA (US); Yatian Qu, Sunnyvale, CA (US); Andrew Lee, Hayward, CA (US); and Michael Christopher De Renzi, Pleasanton, CA (US)
Assigned to Purigen Biosystems, Inc., Pleasanton, CA (US)
Filed by Purigen Biosystems, Inc., Pleasanton, CA (US)
Filed on Apr. 14, 2021, as Appl. No. 17/230,582.
Application 17/230,582 is a division of application No. 16/052,565, filed on Aug. 1, 2018, granted, now 11,041,150.
Claims priority of provisional application 62/541,086, filed on Aug. 3, 2017.
Claims priority of provisional application 62/541,089, filed on Aug. 3, 2017.
Claims priority of provisional application 62/540,515, filed on Aug. 2, 2017.
Prior Publication US 2021/0230576 A1, Jul. 29, 2021
Int. Cl. B01L 3/00 (2006.01); B01L 9/00 (2006.01); C12N 15/10 (2006.01); G01N 27/447 (2006.01)
CPC C12N 15/101 (2013.01) [B01L 3/502738 (2013.01); B01L 3/502746 (2013.01); B01L 3/502761 (2013.01); B01L 3/502776 (2013.01); B01L 3/5085 (2013.01); G01N 27/44717 (2013.01); B01L 9/527 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/0642 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0688 (2013.01); G01N 27/44704 (2013.01); G01N 27/44743 (2013.01); G01N 27/44791 (2013.01)] 27 Claims
OG exemplary drawing
 
1. A fluidic device comprising a fluidic channel and disposed in said fluidic channel a three-dimensional capillary barrier that restricts flow of a liquid in said fluidic channel, wherein said three-dimensional capillary barrier comprises:
a ramp protruding from a surface of said fluidic channel at a first angle;
a plateau surface that is substantially parallel to a wall of said fluidic channel; and
an arcuate cliff surface extending from said plateau surface to said surface of said fluidic channel and wherein said cliff surface intersects with said surface of said fluidic channel at a second angle that is 10 degrees or more steeper than said first angle.