US 11,987,780 B2
L-glass: a novel functionalization method for covalently attaching ECM protein to optical glass
Alexander Laperle, North Hollywood, CA (US); and Clive Svendsen, Pacific Palisades, CA (US)
Assigned to Cedars-Sinai Medical Center, Los Angeles, CA (US)
Appl. No. 16/631,132
Filed by CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US)
PCT Filed Jul. 13, 2018, PCT No. PCT/US2018/042173
§ 371(c)(1), (2) Date Jan. 14, 2020,
PCT Pub. No. WO2019/014644, PCT Pub. Date Jan. 17, 2019.
Claims priority of provisional application 62/532,873, filed on Jul. 14, 2017.
Prior Publication US 2020/0224140 A1, Jul. 16, 2020
Int. Cl. C12M 1/00 (2006.01); C03C 17/30 (2006.01); C03C 23/00 (2006.01); C12M 3/00 (2006.01)
CPC C12M 23/20 (2013.01) [C03C 17/30 (2013.01); C03C 23/006 (2013.01); C12M 3/00 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A method of functionalizing optical glass, comprising:
treating optical glass with oxygen gas plasma;
coating the treated optical glass with a silane; and
attaching a linker to the coated and treated optical glass,
wherein the attached linker is attached to one or more extracellular matrix proteins.