	US 11,987,647 B2
	Cyclic cell-penetrating peptides with one or more hydrophobic residues
Dehua Pei, Columbus, OH (US)
Assigned to Ohio State Innovation Foundation, Columbus, OH (US)
Appl. No. 17/053,684
Filed by Ohio State Innovation Foundation, Columbus, OH (US)
PCT Filed May 9, 2019, PCT No. PCT/US2019/031522 § 371(c)(1), (2) Date Nov. 6, 2020, PCT Pub. No. WO2019/217682, PCT Pub. Date Nov. 14, 2019.
Claims priority of provisional application 62/669,146, filed on May 9, 2018.
Prior Publication US 2021/0070806 A1, Mar. 11, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/64 (2006.01)

CPC C07K 7/64 (2013.01)

1 Claim

1. A complex comprising a cargo moiety and a cyclic peptide, wherein at least one atom of the cyclic peptide or at least one lone pair of the cyclic peptide forms a bond to the cargo moiety; wherein the cargo moiety is one or more therapeutic moieties, one or more targeting moieties, or combinations thereof; and the cyclic peptide is selected from CPP 1-2, CPP 1-3, CPP 1-4, CPP 1-10, CPP 1-11, CPP 1-12, CPP 1-13, CPP 1-14, CPP 1-15, CPP 1-16, CPP 1-17, CPP 1-18, CPP 1-19, CPP 1-20, CPP 1-21, CPP 1-22, CPP 1-23, CPP 1-24, and CPP 1-25.