CPC C07K 16/468 (2013.01) [A61P 1/00 (2018.01); A61P 9/10 (2018.01); A61P 9/14 (2018.01); C07K 16/00 (2013.01); C07K 16/244 (2013.01); C07K 16/245 (2013.01); C07K 16/2863 (2013.01); C07K 16/2887 (2013.01); C07K 16/46 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01); C07K 2319/00 (2013.01)] | 4 Claims |
1. A bispecific antibody, wherein the bispecific antibody binds to IL-18 and IL-1β and comprises:
a first immunoglobulin heavy chain comprising the amino acid sequence SEQ ID NO. 87;
a first immunoglobulin light chain comprising the amino acid sequence SEQ ID NO. 103;
a second immunoglobulin heavy chain comprising the amino acid sequence SEQ ID NO. 55; and
a second immunoglobulin light chain comprising the amino acid sequence SEQ ID No. 71.
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