CPC C07K 16/3069 (2013.01) [A61K 47/6869 (2017.08); A61P 35/04 (2018.01); C07K 2317/51 (2013.01); C07K 2317/56 (2013.01); C07K 2317/72 (2013.01); C07K 2317/94 (2013.01)] | 27 Claims |
1. An isolated antibody or an antigen binding fragment thereof that binds prostate specific membrane antigen (PSMA), the antibody or antigen binding fragment thereof comprising a heavy chain complementarity determining region 1 (HCDR1) comprising the amino acid sequence of RYGMH (SEQ ID NO: 4), a HCDR2 comprising the amino acid sequence of LISYDGSNRYYADSVKG (SEQ ID NO: 5), and a HCDR3 comprising the amino acid sequence of ERESSGWFEGYFDY (SEQ ID NO: 6), and a light chain complementarity determining region 1 (LCDR1) comprising the amino acid sequence of GGNNIGSKSVH (SEQ ID NO: 7), a LCDR2 comprising the amino acid sequence of DNSDRPS (SEQ ID NO: 8), and a LCDR3 comprising the amino acid sequence of QVWDSSSDHVV (SEQ ID NO: 9).
|