CPC C07K 14/4721 (2013.01) [A61K 35/17 (2013.01); A61K 39/00 (2013.01); A61K 39/0005 (2013.01); A61K 39/385 (2013.01); C07K 14/00 (2013.01); C07K 14/47 (2013.01); C07K 14/70539 (2013.01); C07K 14/77 (2013.01); C12N 15/62 (2013.01); A61K 2035/124 (2013.01); A61K 2039/57 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/605 (2013.01); C07K 2319/00 (2013.01)] | 13 Claims |
1. A compound comprising: (a) a soluble Major Histocompatibility Complex (MHC) molecule; and (b) a dynamic anchor comprising Annexin V, wherein the MHC molecule comprises a class I MHC alpha chain comprising the amino acid sequence set forth in SEQ ID NO: 17 or SEQ ID NO: 18, and a β-2 microglobulin polypeptide comprising the sequence set forth in SEQ ID NO: 5 or SEQ ID NO: 6, and
wherein the dynamic anchor comprises the amino acid sequence depicted in SEQ ID NO: 1 or 2.
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