CPC C07D 487/04 (2013.01) [A61P 35/00 (2018.01); C07D 519/00 (2013.01)] | 15 Claims |
1. A method of treating multiple myeloma, comprising:
administering a pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula I or a pharmaceutically acceptable salt thereof:
![]() wherein
R1 is alkyl, heterocyclyl, aryl, or heteroaryl, provided R1 is not cyclohexyl,
R2 is —N═CH-alkyl, —N═CH-aryl or —N═CH-heteroaryl,
R3 and R4 together with the nitrogen to which they are attached form a mono or bi-cyclic heterocyclyl each of the mono or bi-cyclic heterocyclyl is optionally substituted with one, two, three, or four groups selected from C1-C6 alkyl.
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