US 11,987,582 B2
Maleate salts of triazolopyrazine derivatives, compositions, methods of use, and processes of manufacturing the same
Jun Young Choi, Seoul (KR); Kyung Eui Park, Seoul (KR); and Yeong Mun Kim, Seoul (KR)
Assigned to ABION Inc., Seoul (KR)
Filed by ABION Inc, Seoul (KR)
Filed on May 10, 2021, as Appl. No. 17/315,368.
Claims priority of provisional application 63/141,987, filed on Jan. 27, 2021.
Prior Publication US 2022/0235054 A1, Jul. 28, 2022
Int. Cl. C07D 487/04 (2006.01); A61P 35/00 (2006.01)
CPC C07D 487/04 (2013.01) [A61P 35/00 (2018.01)] 38 Claims
 
1. A maleate salt of a triazolopyrazine derivative represented by Chemical Formula 2, wherein the maleate salt has a chemical purity of at least about 4.7% greater than a free base form represented by Chemical Formula 1 after about 15 months at 40 ° C. and 75% relative humidity:

OG Complex Work Unit Chemistry