US 11,987,545 B2
Method for producing m-dialkylbenzaldehyde
Toru Shishimi, Okayama (JP); Tatsuya Utamura, Okayama (JP); Yutaka Matsuura, Niigata (JP); and Tatsuyuki Kumano, Okayama (JP)
Assigned to MITSUBISHI GAS CHEMICAL COMPANY, INC., Chiyoda-ku (JP)
Appl. No. 17/634,097
Filed by MITSUBISHI GAS CHEMICAL COMPANY, INC., Chiyoda-ku (JP)
PCT Filed Jul. 27, 2020, PCT No. PCT/JP2020/028667
§ 371(c)(1), (2) Date Feb. 9, 2022,
PCT Pub. No. WO2021/039230, PCT Pub. Date Mar. 4, 2021.
Claims priority of application No. 2019-153127 (JP), filed on Aug. 23, 2019.
Prior Publication US 2022/0363622 A1, Nov. 17, 2022
Int. Cl. C07C 45/49 (2006.01); C07C 45/50 (2006.01)
CPC C07C 45/50 (2013.01) 20 Claims
 
1. A method for producing m-dialkylbenzaldehyde of formula (3), comprising:
contacting a reaction starting material with carbon monoxide in a presence of a Bronsted acid and a Lewis acid such that the carbon monoxide reacts on the reaction starting material which comprises either 1,4-dialkylbenzene of formula (1), or a mixture of 1,4-dialkylbenzene of the formula (1) and 1,3-dialkylbenzene of formula (2), the mixture comprising 10 mol % or more of the 1,4-dialkylbenzene,

OG Complex Work Unit Chemistry
wherein R1 is a methyl group or an ethyl group, and R2 is a chain or cyclic alkyl group having 3 to 6 carbon atoms and has a tertiary carbon at the benzyl position.