US 11,986,886 B2
Rapid synthesis of metal nanoparticles
Kyuwan Lee, Rexford, NY (US); and Robert H. Singer, New York, NY (US)
Assigned to ALBERT EINSTEIN COLLEGE OF MEDICINE, Bronx, NY (US)
Appl. No. 17/614,843
Filed by Albert Einstein College of Medicine, Bronx, NY (US)
PCT Filed Jun. 5, 2020, PCT No. PCT/US2020/036276
§ 371(c)(1), (2) Date Nov. 29, 2021,
PCT Pub. No. WO2020/247723, PCT Pub. Date Dec. 10, 2020.
Claims priority of provisional application 62/858,047, filed on Jun. 6, 2019.
Prior Publication US 2022/0226891 A1, Jul. 21, 2022
Int. Cl. B22F 9/24 (2006.01); A61K 9/51 (2006.01); B22F 1/054 (2022.01); B22F 1/0545 (2022.01); B22F 1/102 (2022.01); B82Y 5/00 (2011.01); B82Y 15/00 (2011.01); B82Y 40/00 (2011.01)
CPC B22F 9/24 (2013.01) [A61K 9/5115 (2013.01); A61K 9/5192 (2013.01); B22F 1/054 (2022.01); B22F 1/0545 (2022.01); B22F 1/056 (2022.01); B22F 1/102 (2022.01); B22F 2009/245 (2013.01); B82Y 5/00 (2013.01); B82Y 15/00 (2013.01); B82Y 40/00 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A method of making reduced metal nanoparticles, comprising:
mixing a reactive reducing agent with a metal salt in a solution at a temperature of 4-100° C., wherein the reducing agent comprises 3,4-cyclohexenoesculetin-β-D-galactopyranoside or 3,4-cyclohexenoesculetin-β-D-glucoside, or a water-soluble salt thereof; and
forming reduced metal nanoparticles in the solution.