US 11,986,673 B2
Systems and methods for generating radiation treatment plan
Jingjie Zhou, Shanghai (CN); Li Wang, Shanghai (CN); Cheng Ni, Shanghai (CN); Johannes Stahl, Houston, TX (US); and Jonathan Maltz, Houston, TX (US)
Assigned to SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD., Shanghai (CN)
Filed by SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD., Shanghai (CN)
Filed on Jul. 26, 2021, as Appl. No. 17/443,453.
Application 17/443,453 is a continuation of application No. 16/109,707, filed on Aug. 22, 2018, granted, now 11,071,877.
Application 16/109,707 is a continuation of application No. PCT/CN2018/085279, filed on May 2, 2018.
Prior Publication US 2021/0353963 A1, Nov. 18, 2021
Int. Cl. A61N 5/10 (2006.01)
CPC A61N 5/1047 (2013.01) [A61N 5/1031 (2013.01); A61N 5/1045 (2013.01); A61N 5/1081 (2013.01); A61N 2005/1032 (2013.01); A61N 2005/1034 (2013.01); A61N 2005/1035 (2013.01); A61N 5/1036 (2013.01); A61N 5/1039 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method implemented on at least one machine each of which has at least one processor and at least one storage device for determining a radiation treatment plan, the method comprising:
determining a set of one or more optimization goals for radiation delivery by a therapeutic radiation delivery apparatus;
determining a plurality of radiation segments by iteratively optimizing a dose distribution relative to the set of one or more optimization goals,
the determining the plurality of radiation segments by iteratively optimizing the dose distribution relative to the set of one or more optimization goals comprising:
determining a plurality of sections of a rotational movement of a radiation source of the therapeutic radiation delivery apparatus;
determining the plurality of radiation segments based on the plurality of sections by iteratively optimizing a dose distribution relative to the set of one or more optimization goals, comprising:
for each section, determining a fluence map by iteratively optimizing the dose distribution relative to the set of one or more optimization goals, the fluence map corresponding to a plurality of angles within an angle range of the each section;
decomposing the plurality of fluence maps;
determining the plurality of radiation segments based on the plurality of decomposed fluence maps; or
the determining the plurality of radiation segments by iteratively optimizing the dose distribution relative to the set of one or more optimization goals comprising:
determining, based on the plurality of sections, the plurality of radiation segments by optimizing, according to direct aperture optimization, angle ranges, segment shapes, and segment MU values of the plurality of radiation segments in an iterative optimizing operation;
determining a sequence of the plurality of radiation segments for radiation delivery to obtain a delivery trajectory of the radiation source of the therapeutic radiation delivery apparatus;
determining a radiation treatment plan based on the plurality of sequential radiation segments for radiation delivery and the delivery trajectory of the radiation source of the therapeutic radiation delivery apparatus; and
delivering a radiation beam to a target volume based on the radiation treatment plan.