US 11,986,653 B2
Wireless implant for motor function recovery after spinal cord injury
Yi-Kai Lo, Los Angeles, CA (US); Wentai Liu, Los Angeles, CA (US); Victor R. Edgerton, Los Angeles, CA (US); and Chih-Wei Chang, Los Angeles, CA (US)
Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
Filed on Aug. 27, 2021, as Appl. No. 17/459,483.
Application 17/459,483 is a division of application No. 16/043,414, filed on Jul. 24, 2018, granted, now 11,129,983.
Application 16/043,414 is a continuation of application No. PCT/US2017/015435, filed on Jan. 27, 2017.
Claims priority of provisional application 62/287,584, filed on Jan. 27, 2016.
Prior Publication US 2022/0016420 A1, Jan. 20, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01); A61N 1/08 (2006.01); A61N 1/378 (2006.01)
CPC A61N 1/36003 (2013.01) [A61N 1/0551 (2013.01); A61N 1/3787 (2013.01); A61N 1/08 (2013.01)] 10 Claims
OG exemplary drawing
 
1. An implantable epidural spinal stimulator apparatus for motor function recovery, comprising:
(a) an implantable stimulator circuit configured for coupling to a neural network of an organism;
(b) a flexible epidural electrode array coupled to the implantable stimulator circuit comprising a plurality of electrodes;
(c) wherein said implantable stimulator circuit comprises a controller, memory and application software stored in said memory along with one or more stimulation parameters for:
(i) generating one or more electrical pulses for epidural electrical stimulation of inter-neurons within the target treatment region to reengage a neural network connecting the brain and spinal cord;
(ii) receiving bio-impedance data of the target treatment region via the electrode array; and
(iii) performing real time adjustment of the stimulation parameters as a function of the acquired bio-impedance data.