US 11,986,545 B2
Fusion protein comprising growth differentiation factor 11 and epidermal growth factor with enhanced anti-oxidation activity and enhanced skin cell proliferation effect and cosmetic composition for anti-wrinkle comprising the same as effective component
Sun Kyo Lee, Gyeonggi-do (KR); Seong Ran Lee, Gyeonggi-do (KR); Han Bong Ryu, Seoul (KR); and Tae Hyun Kim, Gyeonggi-do (KR)
Assigned to NEXGEN BIOTECHNOLOGIES, INC., Seoul (KR); and Sun Kyo Lee, Gyeonggi-Do (KR)
Appl. No. 17/599,061
Filed by NEXGEN BIOTECHNOLOGIES, INC., Seoul (KR); and Sun Kyo Lee, Gyeonggi-do (KR)
PCT Filed Jun. 1, 2017, PCT No. PCT/KR2017/005751
§ 371(c)(1), (2) Date Sep. 28, 2021,
PCT Pub. No. WO2018/216842, PCT Pub. Date Nov. 29, 2018.
Claims priority of application No. 10-2017-0065257 (KR), filed on May 26, 2017.
Prior Publication US 2022/0160609 A1, May 26, 2022
Int. Cl. A61K 38/00 (2006.01); A61K 8/64 (2006.01); A61Q 19/08 (2006.01); C07K 14/485 (2006.01); C12N 15/70 (2006.01)
CPC A61K 8/64 (2013.01) [A61Q 19/08 (2013.01); C07K 14/485 (2013.01); C12N 15/70 (2013.01); C07K 2319/00 (2013.01); C12N 2800/22 (2013.01)] 19 Claims
 
1. A fusion protein having the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 4.