US 11,986,544 B2
Application for inhibitors of cAMP efflux in body care
Dominique Renee Perez, Albuquerque, NM (US); Larry A. Sklar, Albuquerque, NM (US); and Alexandre Chigaev, Santa Fe, NM (US)
Assigned to UNM RAINFOREST INNOVATIONS, Albuquerque, NM (US)
Appl. No. 17/438,362
Filed by UNM RAINFOREST INNOVATIONS, Albuquerque, NM (US)
PCT Filed Mar. 10, 2020, PCT No. PCT/US2020/021838
§ 371(c)(1), (2) Date Sep. 10, 2021,
PCT Pub. No. WO2020/185746, PCT Pub. Date Sep. 17, 2020.
Claims priority of provisional application 62/816,415, filed on Mar. 11, 2019.
Prior Publication US 2022/0183945 A1, Jun. 16, 2022
Int. Cl. A61K 8/49 (2006.01); A61Q 15/00 (2006.01); A61Q 19/00 (2006.01)
CPC A61K 8/498 (2013.01) [A61Q 15/00 (2013.01); A61Q 19/00 (2013.01)] 4 Claims
OG exemplary drawing
 
1. A method of treating body malodor and/or hyperhidrosis in a subject comprising administering to said subject a composition comprising an effective amount of a cAMP efflux inhibitor in combination with at least one additional cosmetic additive, wherein said cAMP efflux inhibitor is compound according to the chemical structure:

OG Complex Work Unit Chemistry
a pharmaceutically acceptable salt or stereoisomer thereof, or a mixture thereof; and said at least one cosmetic additive is water, an alcohol or other water compatible cosmetically acceptable solvent, a water incompatible solvent, an emollient, a humectant, an oil, a conditioning agent, a surfactant, a thickener/thickening agent, a stiffening agent, an emulsifier, a medicament, a fragrance, a preservative, a deodorant component, an antiperspirant compound, a skin protecting agent, a pigment, a dye, a coloring agent, a preservative or a mixture thereof.