US 11,986,530 B2
Drug composition for parenteral administration
Hideaki Kakeya, Kyoto (JP); Masashi Kanai, Kyoto (JP); Nobuaki Takahashi, Kyoto (JP); Tadashi Hashimoto, Meguro-ku (JP); Atsushi Imaizumi, Hino (JP); and Hitomi Ozawa, Yokohama (JP)
Assigned to THERABIOPHARMA INC., Kawasaki (JP); and KYOTO UNIVERSITY, Kyoto (JP)
Filed by THERABIOPHARMA INC., Kawasaki (JP); and KYOTO UNIVERSITY, Kyoto (JP)
Filed on Apr. 27, 2020, as Appl. No. 16/858,810.
Application 16/858,810 is a division of application No. 16/313,252, previously published as PCT/JP2017/023753, filed on Jun. 28, 2017.
Claims priority of application No. 2016-128889 (JP), filed on Jun. 29, 2016.
Prior Publication US 2020/0254105 A1, Aug. 13, 2020
Int. Cl. A61K 47/54 (2017.01); A61K 9/00 (2006.01); A61K 31/12 (2006.01); A61K 31/185 (2006.01); A61K 31/223 (2006.01); A61K 31/7028 (2006.01); A61K 38/00 (2006.01); A61P 3/06 (2006.01); A61P 9/00 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/08 (2006.01)
CPC A61K 47/549 (2017.08) [A61K 9/0019 (2013.01); A61K 31/12 (2013.01); A61K 31/185 (2013.01); A61K 31/223 (2013.01); A61K 31/7028 (2013.01); A61K 38/00 (2013.01); A61P 3/06 (2018.01); A61P 9/00 (2018.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/08 (2018.01)] 1 Claim
 
1. A method of administering curcumin to a subject to maintain a pharmacological concentration of free curcumin in the subject's blood, comprising intravenously administering an aqueous solution comprising curcumin monoglucuronide wherein the concentration of free curcumin in the blood achieved thru IV administration is greater than the that achieved by oral administration of curcumin.