US 11,986,506 B2
Dietary supplements for inhibiting PDE5 and increasing cGMP levels
Ganga Raju Gokaraju, Vijaywada (IN); Rama Raju Gokaraju, Vijayawada (IN); Trimurtulu Golakoti, Vijayawada (IN); Kiran Bhupathiraju, Vijayawada (IN); Venkata Kanaka Ranga Raju Gokaraju, Vijayawada (IN); Krishanu Senguptha, Vijayawada (IN); and Venkata Krishna Raju Alluri, Vijayawada (IN)
Assigned to LAILA NUTRACEUTICALS, Vijayawada (IN)
Appl. No. 16/479,798
Filed by LAILA NUTRACEUTICALS, Vijayawada (IN)
PCT Filed Jan. 19, 2018, PCT No. PCT/IN2018/050028
§ 371(c)(1), (2) Date Jul. 22, 2019,
PCT Pub. No. WO2018/134848, PCT Pub. Date Jul. 26, 2018.
Claims priority of application No. 201741002329 (IN), filed on Jan. 20, 2017.
Prior Publication US 2021/0338757 A1, Nov. 4, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 36/22 (2006.01); A23L 33/105 (2016.01); A61K 9/00 (2006.01); A61K 36/38 (2006.01); A61K 45/06 (2006.01); A61P 15/10 (2006.01)
CPC A61K 36/22 (2013.01) [A23L 33/105 (2016.08); A61K 9/0095 (2013.01); A61K 36/38 (2013.01); A61K 45/06 (2013.01); A61P 15/10 (2018.01); A61K 2236/15 (2013.01); A61K 2236/333 (2013.01); A61K 2236/51 (2013.01); A61K 2236/53 (2013.01)] 18 Claims
 
1. An herbal composition, comprising at least two extracts selected from the group consisting of an extract of a fruit rind of Punica granatum, a bark or leaf extract of Mangifera indica, and an extract of a fruit rind of Garcinia mangostana;
wherein the herbal composition comprises:
a mixture of the extract of the fruit rind of Punica granatum and the bark or leaf extract of Mangifera indica in a ratio ranging from 3:1 to 1:3;
a mixture of the extract of the fruit rind of Punica granatum and the extract of the fruit rind of Garcinia mangostana in a ratio ranging from 3:1 to 1:3;
a mixture of the bark or leaf extract of Mangifera indica and the extract of the fruit rind of Garcinia mangostana in a ratio ranging from 3:1 to 1:3; or
a combination thereof;
wherein each of the at least two extracts is an alcoholic or hydroalcoholic extract.