	US 11,986,496 B2
	Targeting B cell activating factor receptor (BAFF-R) using ligand-based chimeric antigen receptor (CAR)-T cells
Reshmi Parameswaran, Solon, OH (US)
Assigned to CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US)
Filed by Case Western Reserve University, Cleveland, OH (US)
Filed on Jun. 1, 2020, as Appl. No. 16/888,989.
Claims priority of provisional application 62/980,727, filed on Feb. 24, 2020.
Claims priority of provisional application 62/908,795, filed on Oct. 1, 2019.
Claims priority of provisional application 62/855,130, filed on May 31, 2019.
Prior Publication US 2020/0376032 A1, Dec. 3, 2020
Int. Cl. A61K 35/17 (2015.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61P 35/02 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01)

CPC A61K 35/17 (2013.01) [A61K 38/177 (2013.01); A61K 38/1774 (2013.01); A61K 45/06 (2013.01); A61P 35/02 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70575 (2013.01); C07K 14/70578 (2013.01); C07K 16/2803 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01)]

13 Claims

1. A chimeric receptor for targeting a receptor for B cell activating factor (BAFF) comprising an amino acid sequence with at least 95% sequence identity to SEQ ID NO: 20.