	US 11,986,472 B1
	Method of controlling alcohol consumption in subjects treated for opioid dependence
Michael John Sumner, Malvern, PA (US)
Assigned to OREXO AB, Uppsala (SE)
Filed by OREXO AB, Uppsala (SE)
Filed on Jun. 30, 2021, as Appl. No. 17/363,860.
Claims priority of provisional application 63/046,249, filed on Jun. 30, 2020.
Int. Cl. A61K 31/485 (2006.01); A61K 9/00 (2006.01); G16H 20/70 (2018.01)

CPC A61K 31/485 (2013.01) [A61K 9/006 (2013.01); G16H 20/70 (2018.01)]

8 Claims

1. A method of treating opioid dependence in a patient, wherein the patient is concurrently consuming alcohol, the method comprising:

administering a sublingual dose of buprenorphine and naloxone to the patient in a treatment regimen effective to manage the patient's withdrawal symptoms and cravings for an opioid; and

in conjunction with the administration of the sublingual dose of buprenorphine and naloxone, engaging with a self-directed digital, interactive cognitive behavioral therapy program that reduces alcohol consumption,

wherein the alcohol consumption by the patient is reduced, thereby increasing adherence by the patient to the treatment regimen.