US 11,986,460 B2
Solid pharmaceutical preparation containing lipoic acid and use thereof
Satishkumar Jain, Thane (IN); Parminder Singh Sidhu, Darmstadt (DE); Paul Robinson, East Yorkshire (GB); Madhura Rege, Mumbai (IN); and Sundareswarakumar Chellaswamy, Tamil Nadu (IN)
Assigned to The Procter & Gamble Company, Cincinnati, OH (US)
Filed by The Procter & Gamble Company, Cincinnati, OH (US)
Filed on Nov. 26, 2019, as Appl. No. 16/695,710.
Claims priority of application No. 201831044436 (IN), filed on Nov. 26, 2018.
Prior Publication US 2020/0163934 A1, May 28, 2020
Int. Cl. A61K 31/385 (2006.01); A61K 47/02 (2006.01); A61K 47/22 (2006.01); A61K 47/24 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01)
CPC A61K 31/385 (2013.01) [A61K 47/02 (2013.01); A61K 47/22 (2013.01); A61K 47/24 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01)] 15 Claims
 
1. A solid pharmaceutical preparation comprising (i) a safe and effective amount of lipoic acid as active agent, (ii) a stabilizer comprising dicalcium phosphate, (iii) a binder comprising a vinylpyrrolidone-vinyl acetate copolymer, wherein the lipoic acid and the binder are present in relation to each other in a weight ratio of from about 1:0.08 to about 1:0.03.