US 11,986,459 B2
Methods for the treatment of Mycobacterium infections
Bill J. Baker, Temple Terrace, FL (US); Kyle Rohde, Orlando, FL (US); Bingjie Yang, Temple Terrace, FL (US); and Marisa Fuse, Winter Springs, FL (US)
Assigned to University of South Florida, Tampa, FL (US); and UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC., Orlando, FL (US)
Filed by University of South Florida, Tampa, FL (US)
Filed on Apr. 5, 2022, as Appl. No. 17/713,576.
Application 17/713,576 is a continuation of application No. 17/375,403, filed on Jul. 14, 2021, abandoned.
Claims priority of provisional application 63/051,476, filed on Jul. 14, 2020.
Prior Publication US 2022/0226284 A1, Jul. 21, 2022
Int. Cl. A61K 31/12 (2006.01); A61K 31/133 (2006.01); A61K 31/145 (2006.01); A61K 31/192 (2006.01); A61K 31/235 (2006.01); A61K 31/343 (2006.01); A61K 31/352 (2006.01); A61K 31/365 (2006.01); A61K 31/366 (2006.01); A61K 31/4015 (2006.01); A61K 31/4045 (2006.01); A61K 31/44 (2006.01); A61K 31/4409 (2006.01); A61K 31/454 (2006.01); A61K 31/472 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 31/505 (2006.01); A61K 31/7036 (2006.01); A61P 31/06 (2006.01)
CPC A61K 31/366 (2013.01) [A61K 31/12 (2013.01); A61K 31/133 (2013.01); A61K 31/145 (2013.01); A61K 31/192 (2013.01); A61K 31/235 (2013.01); A61K 31/343 (2013.01); A61K 31/352 (2013.01); A61K 31/365 (2013.01); A61K 31/4015 (2013.01); A61K 31/4045 (2013.01); A61K 31/44 (2013.01); A61K 31/4409 (2013.01); A61K 31/454 (2013.01); A61K 31/472 (2013.01); A61K 31/496 (2013.01); A61K 31/498 (2013.01); A61K 31/505 (2013.01); A61K 31/7036 (2013.01); A61P 31/06 (2018.01)] 10 Claims
 
1. A method of treating an infection with a Mycobacterium in a subject comprising administering to the subject a therapeutically effective amount of a compound of Formula IX

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.