US 11,986,384 B2
Composite scaffold for the repair, reconstruction, and regeneration of soft tissues
Kevin A. Rocco, New Haven, CT (US); Bhavana Mohanraj, Philadelphia, PA (US); Jeffrey Ott, New Haven, CT (US); Justin Bendigo, Reading, PA (US); Jacob Edward Komenda, New Haven, CT (US); Mark Theodore Aronson, Midlothian, VA (US); and Andrew James Carter, Stow, MA (US)
Assigned to Biorez, Inc., New Haven, CT (US)
Filed by Biorez, Inc., New Haven, CT (US)
Filed on Jul. 8, 2020, as Appl. No. 16/923,782.
Application 16/923,782 is a continuation of application No. 16/785,490, filed on Feb. 7, 2020, granted, now 11,712,332.
Claims priority of provisional application 62/970,620, filed on Feb. 5, 2020.
Claims priority of provisional application 62/802,391, filed on Feb. 7, 2019.
Prior Publication US 2020/0337828 A1, Oct. 29, 2020
Int. Cl. A61F 2/08 (2006.01); A61F 2/00 (2006.01); A61L 27/14 (2006.01); A61L 27/18 (2006.01); A61L 27/24 (2006.01); A61L 27/26 (2006.01); A61L 27/48 (2006.01); A61L 27/52 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); D06N 3/00 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); D04B 21/12 (2006.01)
CPC A61F 2/08 (2013.01) [A61F 2/0063 (2013.01); A61L 27/14 (2013.01); A61L 27/18 (2013.01); A61L 27/24 (2013.01); A61L 27/26 (2013.01); A61L 27/48 (2013.01); A61L 27/52 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); D06N 3/0043 (2013.01); A61F 2002/0068 (2013.01); A61F 2002/0081 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0057 (2013.01); A61F 2210/0061 (2013.01); A61F 2210/0076 (2013.01); A61F 2240/001 (2013.01); A61L 27/34 (2013.01); A61L 27/50 (2013.01); A61L 2430/10 (2013.01); D04B 21/12 (2013.01); D10B 2509/08 (2013.01); Y10T 428/249921 (2015.04); Y10T 428/249978 (2015.04); Y10T 442/2484 (2015.04); Y10T 442/419 (2015.04)] 32 Claims
OG exemplary drawing
 
1. A composite scaffold comprising:
a microporous matrix having a multitude of interconnected pores opening to an exterior surface of the microporous matrix and collectively defining void space; and
a three-dimensional, textile structure supporting the microporous matrix and comprising first and second outer layers separated by an interior space therebetween and the microporous matrix within the interior space, and a plurality of spacer yarns extending through the interior space and attached to each of the first and second outer layers;
wherein a surface area of the composite scaffold is between approximately 0.3 m2/gram and 15.0 m2/gram per gram of the composite scaffold.