US 11,986,319 B2
Patch guide method and program
Dong Hyeon Kim, Seoul (KR); and Jun Kil Been, Seoul (KR)
Assigned to NEUROPHET Inc., Gwangju (KR)
Filed by NEUROPHET Inc., Gwangju (KR)
Filed on May 4, 2021, as Appl. No. 17/307,179.
Application 17/307,179 is a continuation in part of application No. 15/688,005, filed on Aug. 28, 2017, granted, now 11,116,404.
Claims priority of application No. 10-2017-0108056 (KR), filed on Aug. 25, 2017.
Prior Publication US 2021/0267547 A1, Sep. 2, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/00 (2006.01); A61B 5/055 (2006.01); A61N 1/04 (2006.01)
CPC A61B 5/684 (2013.01) [A61B 5/0036 (2018.08); A61B 5/0042 (2013.01); A61B 5/0077 (2013.01); A61B 5/055 (2013.01); A61N 1/0492 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A patch guide method comprising:
acquiring a 3-dimensional scan model including a head of an object by using a depth camera, by a computer;
acquiring a 3-dimensional brain MRI model of the object;
matching the 3-dimensional scan model and the 3-dimensional brain MRI model t acquire a matched model;
acquiring an image captured by photographing the head of the object by using the depth camera;
matching one location of the captured image and one location on the matched model; and
determining a location of at least one patch configured to be attached to the head of the object, by using a 3-dimensional brain map,
wherein the acquiring of the 3-dimensional brain MRI model of the object includes:
acquiring a brain MRI image of the object;
acquiring physical characteristics of a plurality of areas included in the brain MRI image, the physical characteristics including isotropic electrical conductivities of the plurality of areas and/or anisotropic electrical conductivities of the plurality of areas; and
generating the 3-dimensional brain map of the object based on the acquired physical characteristics of the plurality of areas included in the brain MRI image, and
wherein the determining the location of the at least one patch includes:
acquiring a target stimulus point, to which an electrical stimulus is to be applied in a brain of the object, by using the 3-dimensional brain map, wherein the electrical stimulus is applied by using a current generated by an electrode included in the at least one patch;
performing a simulation of a delivery process of the electrical stimulus to the target stimulus point from a plurality of candidate stimulus positions, wherein the simulation is for a case where the electrode included in the at least one patch is attached to the plurality of candidate stimulus positions; and
determining the location of the at least one patch by using a result of the simulation.